Alpha Gal is a sugar (galactose-alpha-1,3-galactose) found in most mammals with the exception of humans, apes, and monkeys. Alpha-gal can be found in many products made from mammals including some medications, cosmetics, vaccines, gelatin, and milk products.

Although it was initially presumed that the lone Star tick transmitted alpha-gal, it is now evident that other ticks can also transmit it. This is in consideration of the fact that alpha-gal exists in Australia and Europe where the lone star tick has not been found. Alpha gal is transmitted to star ticks after biting animals including cows and sheep. Ticks will then carry the alpha gal and inject the molecules into the human body. This may trigger the appearance of a condition known as the alpha-gal syndrome. This results from an unusual immune response to the alpha gal sugar. Affected people would have mild to severe allergic reactions upon eating red meat (beef, lamb, pork, venison, and rabbits). Allergic reactions also occur upon exposure to products from mammals such as cosmetics, medications, vaccines, gelatin, and milk products. Cetuximab, a cancer drug, contains alpha-gal. More serious reactions can develop in people suffering from repeated tick bites. Symptoms do not necessarily develop after each exposure and naturally symptoms vary from one individual to another. Alpha gal allergies appear to affect individuals of all ages. It is mostly common in south eastern and mid-western United States, though many cases have been identified in other parts of the country where the lone star tick is not typically seen.

Symptoms

Symptoms include hives, itching, eczema, dizziness, fainting, breathing difficulties, and drop in blood pressure. Other symptoms include; swelling of the lips, face, tongue and throat, or other body parts. A runny nose, sneezing, and headaches are also common. Gastro-intestinal symptoms such as abdominal pain, diarrhea, nausea or vomiting are not uncommon. While reactions to the majority food allergies are seen almost immediately following food ingestion, alpha-gal allergy can be delayed up to eight hours following the consumption of red meat. This is due to the fact that alpha-gal molecules take a longer time to be digested and absorbed compared to other allergens.

In the extreme cases, patients may develop alpha-gal anaphylactic shock. This is a serious medical emergency that require immediate medical attention and treatment with epinephrine (adrenaline) injector such as EpiPen. Signs of anaphylaxis concludes; drop in blood pressure, swelling of the mouth and the throat, airway constriction, dizziness, and loss of consciousness.

Course of the disease

Unless the individual is repeatedly bitten by ticks, it is believed that alpha-gal allergy may dissipate on its own in about 3 to 5 years.

Tests

Similar to other allergies, skin tests through pricking the skin with a small amount of alpha-gal can identify reactions to the sugar in allergic patients. Identifying alpha-gal antibodies in the bloodstream is an additional method.

Medical treatment

Avoid wooded bushy areas with long grass where ticks are usually found. Appropriate clothes should be worn in such areas. Use of appropriate insect repellent is advised. Clearing brush and leaves would deprive the ticks from their favorable habitat. After trips to wooded grassy areas, showering may help remove unattached ticks. Ticks usually stay unattached to the skin for hours.

Patients diagnosed with Alpha-gal will have to avoid eating red meat, dairy, and other products that contain Alpha-gal. Medical treatment of allergic reactions is mainly symptomatic in nature. Antihistamines and steroids are frequently recommended. EpiPen and other measures are needed for alpha-gal anaphylactic shock.

How we can help

Various methods of acupuncture have been used to help ameliorate the various symptoms of alpha-gal allergies. At this center, a very unique approach of acupuncture treatment introduced by Dr. Nader Soliman (patent pending) has proved to be the Pinnacle of all known acupuncture approaches. Soliman Auricular Allergy Treatment (SAAT), as it is known, is a simple technique using only one needle and requires only one treatment. This technique has proven to provide the strongest relief from alpha-gal allergy symptoms among all known acupuncture techniques.